| Crosbi ID | 638773 |
| Bib IRB ID | 831838 |
| Year | 2016 |
| Status | neobjavljeno |
| Type | prilog sa skupa (neobjavljen) |
| Subtype | neobjavljeni prilog sa skupa |
| Authors | Leščić Ašler, Ivana; Štefanić, Zoran; Luić, Marija |
en original Insights into catalytic mechanism of an enzyme
Investigation of the mechanism of enzyme action is maybe the most important aspect of protein research. There is a plethora of methods available to study interactions of an enzyme with its substrates and/or inhibitors. Among those, X-ray crystallography stands out by giving the precise 3D picture of enzyme's active site. In principle, the higher the power of X-rays, the higher the resolution of protein's 3D-structure and more details to be observed. Synchrotrons, as the most powerful X- ray sources, provide in many cases atomic resolution 3D-structures and enable detection of details that could otherwise be obscured. The superiority of synchrotron over in-house X- ray source in study of enzyme's active site will be demonstrated on several protein examples.
en original X-ray crystallography ; synchrotron radiation ; enzymes ; mechanism of action
Leščić Ašler, Ivana; Štefanić, Zoran; Luić, Marija Insights into catalytic mechanism of an enzyme // XVI International Conference on Science, Arts and Culture, INTERNATIONAL CONFERENCE ON SESAME In honour of Paolo Budinich Veli Lošinj, Hrvatska, 29.08.2016-02.09.2016