The series of compounds was tailored to possess donor and acceptor functionalities for intensive hydrogen bonding that leads to supramolecular assemblies. For this purpose the peptide bonds of amino acids linked to different spacers are useful sintons. To spatially orient hydrogen bonds, the terminal carboxylic groups were esterified. (SS)-phthaloyl-bis-(leucine methyl ester) (1), (SS)-terephthaloyl-bis-(leucine methyl ester) (2) and its valine analogue (3) were synthesized and their crystal packings analysed. It is interesting that amino acid residue, in this case leucine, defines the space group P 21 (compounds 1 and 2) whereas terephthaloyl spacer determines the system of hydrogen bonds (compounds 2 and 3). Thus, the crystal packing of compound 1 reveals the one dimensional α-network (as defined by Fowler and Lauher ) whereas 2 and 3 form the two-dimensional β-network.